Generation of an erythroid progenitor-derived iPSC line, VRISGi002-A, from a healthy 27-year-old Vietnamese donor under a feeder-free system

Generation of an erythroid progenitor-derived iPSC line, VRISGi002-A, from a healthy 27-year-old Vietnamese donor under a feeder-free system

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We have established the footprint-free Vietnamese human induced pluripotent stem cell (hiPSC) line, VRISGi002-A, from CD71 + CD235a + erythroid progenitor cells (EPCs) of a 27-year-old healthy donor.The EPCs were enriched from isolated peripheral blood and reprogrammed using Sendai viruses which carried the reprogramming factors c-MYC, SOX2, Touch Screen Console KLF4, and OCT4 under a feeder-free culture system.The established VRISGi002-A cell line expressed typical pluripotency markers, displayed a normal karyotype, and demonstrated the Other Diet and Weight Loss Products potential to differentiate into the three germ layers.This hiPSC line could serve as a Vietnamese healthy control model for physiological processes and drug screening.